Caveolae are submicroscopic, plasma membrane pits that are abundant in many mammalian cell types. The past few years have seen a quantum leap in our. Caveolae as plasma membrane sensors, protectors and organizers. Caveolae at the plasma membrane can be removed by endocytosis to. membrane reservoirs that buffer the cellular adaptation to mechanical stress. “ Caveolae as Plasma Membrane Sensors, Protectors and Organizers.” Nature.
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What is this page? Caveolae are submicroscopic, plasma membrane pits that are abundant in many mammalian cell types. The past few years have seen a quantum leap in our understanding organizerd the formation, dynamics and functions of these enigmatic structures.
Caveolae as plasma membrane sensors, protectors and organizers
Caveolae have now emerged as vital plasma membrane sensors that can respond to plasma membrane stresses and remodel the extracellular environment.
Caveolae at the plasma membrane can be removed by endocytosis to regulate their surface density or can be disassembled and their structural components degraded.
Coat proteins, called cavins, work together with caveolins to regulate the formation of caveolae but also have the potential to dynamically transmit signals that originate in cavolae to various cellular destinations.
The importance of caveolae as protective elements in the plasma membrane, and as membrane organizers and sensors, is highlighted by links between caveolae dysfunction and human diseases, including muscular dystrophies and cancer.
This page is provided by Altmetric. Caveolae as plasma membrane sensors, protectors and organizers Overview of attention for article published in Nature Reviews Molecular Cell Biology, February High Attention Score compared to outputs of the same age and source 86th percentile. Mentioned by twitter 2 tweeters facebook 1 Facebook page wikipedia 1 Wikipedia page. Readers plsma mendeley Mendeley citeulike cveolae CiteULike.
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What is caveolar endocytosis? | MBInfo
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